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If you have done your research to carefully select a dog that's right for you and discover several breeds fit your lifestyle, it can never be a bad idea to get a mixed breed from a shelter. Many times mixed breeds are free from the health issues that plague their purebred counterparts in closed breeding circles.
In fact, the so-called 'designer dogs' such as the Cockapoo, ChiWeenie, etc. are basically mixed breeds! Two purebred parents of different breeds still produce a mixed breed puppy despite the fancy marketing term and added purchase price.
If you're getting a mixed breed from a shelter, you have the added advantage that many of these dogs have had basic canine obedience and socialization. Unless you are getting a puppy, you also will be privy to information about the dog's personality, particular likes and dislikes. Your adoption fee will also be much less than the cost of buying a purebred puppy from a breeder. And the best part is that you'll be giving a canine a new home.